- Jun 17 Sat 2017 15:55
Molecular pathology of lung cancer
- Jun 17 Sat 2017 14:34
Biology of lung cancer
G1->S phase: (1) suppressor (RB pathway, 和CDK相關!),(2) suppressor (p53 pathway)
Resistance to cell death (apoptosis): 主要是和p53有關
- May 27 Sat 2017 11:20
Interstitial lung disease with autoimmune disease
ILD in IM: anti-JO-1(+) -> 70% (anti-MDA5)
(IM: inflammatory myositis; Gottron's papules, mechanical hand )
- Mar 22 Wed 2017 21:46
肺癌筆記
1. IV NVB最多給到BSA 20-25, 若給到35,則容易severe neutropenia
2. 第一次打immunotherapy, 最好把時間拉長到90分鐘,不然容易anaphylactic shock, 可加0.5 amp Vena
- May 21 Sat 2016 12:31
從浩鼎學習Globo H-Based Vaccine
目前是immunotherapy對於lung cancer治療的新進程,從之,我們可以相較於breast cancer的浩鼎小故事。
原來它的疫苗是用fully synthetic glycoconjugate vaccine composed of globo H and monophosphoryl lipid A (MPLA) 來induce T cell immunity。而且他的primary end point是PFS. 今天老師上課說,目前美國FDA希望要用OS來評估,而不是用PFS。
- Jan 13 Wed 2016 18:36
抽完胸水後可以坐飛機嗎?(pneumothorax post thoracentesis)
- Nov 03 Tue 2015 19:42
pulmonary embolism 肺栓塞 病生理機轉
引自Harrison's Principles of Internal Medicine, 19e chap. 300: Deep Venous Thrombosis and Pulmonary Thromboembolism
某次內專有考這一題,pulmonary embolism的機轉:
- Oct 30 Fri 2015 17:50
Vemurafenib in non-melanoma patient (NEJM 2015)
今天早上Chief ground時學弟分享的新藥, Vemurafenib:
- Sep 25 Fri 2015 21:37
Idiopathic acute eosinophilic pneumonia
1. 首先在1989年,於acute resp. failure的case中被描述。
2. AEP與CEP不同,雖然都是肺實質有eosinophilic infiltration
- Apr 04 Sat 2015 01:12
非肺部手術之術前評估
寫這一篇文章,專門是對於骨科會診用的 = =;
PPCs(術後肺部併發症)會延長住院時間(廢話),如pneumonia, atelectasis, respiratory failure, bronchospasm and exacerbation of underlying chronic lung disease.